Wurm K
Fortschr Med. 1982 Sep 9;100(34):1560-3.
According to today's knowledge the definition of sarcoidosis is formulated as follows: Sarcoidosis is a systemic disorder induced by inhalation, to be interpreted as a reactionary disease with genetic predisposition. The inducing noxa are still unknown. Sarcoidosis is characterized: a) by its specific course appearing as radiologically visible stages, b) immunologically by a disturbed balance between cellular and humoral defence reaction, c) in view of the pathological anatomy by the epitheloid cell granuloma. The clinical pictures have to be differentiated between two forms of this disease: an acute course and an asymptomatically starting chronic course. The clinical phenomenology shows great variety as to the course and the predominantly injured organs. Concerning the nature of sarcoidosis nevertheless we have a precise idea today. The diagnosis is in most cases without problems. Corticoid therapy is the only effective treatment.
根据当今的知识，结节病的定义如下：结节病是一种由吸入引起的全身性疾病，可被解释为具有遗传易感性的反应性疾病。诱发因素仍然未知。结节病的特征为：a）其特定病程表现为放射学上可见的阶段；b）在免疫学方面，细胞和体液防御反应之间的平衡受到干扰；c）从病理解剖学角度看，表现为上皮样细胞肉芽肿。这种疾病的临床表现必须区分两种形式：急性病程和无症状起病的慢性病程。临床现象学在病程和主要受累器官方面表现出极大的多样性。然而，关于结节病的本质，我们如今已有确切的认识。在大多数情况下，诊断并无问题。皮质类固醇疗法是唯一有效的治疗方法。
