Schall G L, McDonald H D, Carr L B, Capozzi A
JAMA. 1978 Nov 24;240(22):2441-5.
The use of xenon Xe 133 ventilation-perfusion lung scans for the early diagnosis of inhalation injury was evaluated in 67 patients with acute thermal burns. Study results were interpreted as normal if there was complete pulmonary clearance of the radioactive gas by 150 seconds. Thirty-two scans were normal, 32 abnormal, and three technically inadequate. There were three true false-positive study results and one false-negative study result. Good correlation was found between the scan results and various historical, physical, and laboratory values currently used to evaluate inhalation injury. The scans appeared to be the most sensitive method for the detection of early involvement, often being abnormal several days before the chest roentgenogram. Xenon lung scanning is a safe, easy, accurate, and sensitive method for the early diagnosis of inhalation injury and has important therapeutic and prognostic implications as well.
对67例急性热烧伤患者使用氙Xe 133通气灌注肺扫描评估吸入性损伤的早期诊断。如果放射性气体在150秒内完全从肺部清除，研究结果被解释为正常。32次扫描结果正常，32次异常，3次技术上不充分。有3例假阳性研究结果和1例假阴性研究结果。扫描结果与目前用于评估吸入性损伤的各种病史、体格检查和实验室值之间存在良好的相关性。扫描似乎是检测早期受累的最敏感方法，通常在胸部X线片出现异常前几天就表现为异常。氙肺扫描是一种安全、简便、准确且敏感的吸入性损伤早期诊断方法，对治疗和预后也具有重要意义。
