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用转移因子治疗播散性隐球菌病。

Disseminated Cryptococcus treated with transfer factor.

作者信息

Gross P A, Patel C, Spitler L E

出版信息

JAMA. 1978 Nov 24;240(22):2460-2.

PMID:712939
Abstract

Cardiac toxic reactions and pulmonary consolidation in the left lower lobe developed in a patient who was receiving amphotericin B therapy for cryptococcal meningitis. Following surgical resection of the lobe, multiple subcutaneous cryptococcal abscesses appeared. Flucytosine administered intravenously failed to eradicate the lesions. Transfer factor therapy and multiple drainage procedures elimniated the skin abscesses. Transfer factor therapy was administered for one year; the patient was asymptomatic 16 months after therapy was discontinued.

摘要

一名因隐球菌性脑膜炎接受两性霉素B治疗的患者出现了心脏毒性反应和左下叶肺实变。在该叶进行手术切除后,出现了多个皮下隐球菌脓肿。静脉注射氟胞嘧啶未能根除这些病变。转移因子疗法和多次引流手术消除了皮肤脓肿。转移因子疗法持续了一年;在治疗停止16个月后,患者无症状。

相似文献

1
Disseminated Cryptococcus treated with transfer factor.用转移因子治疗播散性隐球菌病。
JAMA. 1978 Nov 24;240(22):2460-2.
2
Disseminated cryptococcosis after transurethral resection of the prostate.经尿道前列腺切除术后播散性隐球菌病
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Granulocytopenia and thrombocytopenia associated with combination therapy of amphotericin B and low-dose flucytosine in a patient with cryptococcal meningitis.一名患有隐球菌性脑膜炎的患者在接受两性霉素B与小剂量氟胞嘧啶联合治疗时出现粒细胞减少和血小板减少。
DICP. 1989 Sep;23(9):672-4. doi: 10.1177/106002808902300910.
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[Special therapeutic aspects of cryptococcal meningoencephalitis].[新型隐球菌性脑膜脑炎的特殊治疗方面]
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Cryptococcal meningitis treated with 5-fluorocytosine and amphotericin B.用5-氟胞嘧啶和两性霉素B治疗的隐球菌性脑膜炎。
Isr J Med Sci. 1974 Sep;10(9):1148-52.
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Therapy of cryptococcosis with a combination of flucytosine and amphotericin B.用氟胞嘧啶和两性霉素B联合治疗隐球菌病。
J Infect Dis. 1975 Oct;132(4):368-73. doi: 10.1093/infdis/132.4.368.
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Ocular cryptococcosis in New Zealand.新西兰的眼部隐球菌病。
N Z Med J. 1980 Apr 23;91(658):291-3.
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Efficacy of amphotericin B in combination with flucytosine against flucytosine-susceptible or flucytosine-resistant isolates of Cryptococcus neoformans during disseminated murine cryptococcosis.两性霉素B联合氟胞嘧啶对播散性小鼠新型隐球菌病中氟胞嘧啶敏感或耐药分离株的疗效。
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Treatment of cryptococcal meningitis with five anti-fungal drugs: the role of amphotericin B.使用五种抗真菌药物治疗隐球菌性脑膜炎:两性霉素B的作用
Drugs Exp Clin Res. 1990;16(7):327-32.
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Resolution of cryptococcal meningitis and associated granuloma lung with antifungal therapy: report of a case.抗真菌治疗使隐球菌性脑膜炎及相关肺部肉芽肿消退:一例报告
Indian J Chest Dis Allied Sci. 1994 Jul-Sep;36(3):153-8.

引用本文的文献

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Pleural fluid secondary to pulmonary cryptococcal infection: a case report and review of the literature.肺隐球菌感染继发胸腔积液:病例报告及文献复习。
BMC Infect Dis. 2019 Aug 12;19(1):710. doi: 10.1186/s12879-019-4343-2.
2
Dialysable leukocyte extracts modify the course of experimental paracoccidioidomycosis in the Syrian hamster.可透析白细胞提取物改变叙利亚仓鼠实验性副球孢子菌病的病程。
Mycopathologia. 1993 Mar;121(3):149-56. doi: 10.1007/BF01104070.
3
Fatal cryptococcosis in a patient with chronic renal failure: a case report.
一名慢性肾衰竭患者的致命性隐球菌病:病例报告
J Natl Med Assoc. 1980 Apr;72(4):374-6.