Rein A J, Sapoznikov D, Lewis N, Halon D A, Gotsman M S, Lewis B S
Int J Cardiol. 1982;2(1):61-70. doi: 10.1016/0167-5273(82)90010-9.
We studied regional left ventricular contraction patterns and ejection fraction from real-time two-dimensional echocardiograms in 8 normal subjects, 11 patients with coronary artery disease and 2 with congestive cardiomyopathy. The ventricle was divided into 12 regions and for each region, we calculated ejection fraction using a method which integrated the incremental volumes of a series of hemicylinders constructed within that region. The data obtained were displayed graphically to provide a detailed picture of regional ventricular function. Normal subjects had a uniform regional ventricular pattern (regional ejection fraction 54-74%). In patients with coronary disease, we found varying degrees of regional ventricular contraction abnormalities. In congestive cardiomyopathy global hypokinesis was present, and regional ejection fraction was reduced in all areas (11-39%). The study showed that two-dimensional echocardiography is a useful non-invasive bedside technique which may provide detailed quantitative information relating to regional left ventricular contraction abnormalities.
我们对8名正常受试者、11名冠状动脉疾病患者和2名充血性心肌病患者进行了实时二维超声心动图检查，研究了左心室局部收缩模式和射血分数。将心室分为12个区域，对于每个区域，我们使用一种方法计算射血分数，该方法整合了在该区域内构建的一系列半圆柱体的增量体积。获得的数据以图形方式显示，以提供心室局部功能的详细图像。正常受试者具有均匀的心室局部模式（局部射血分数为54 - 74%）。在冠心病患者中，我们发现了不同程度的心室局部收缩异常。在充血性心肌病中，存在整体运动减弱，所有区域的局部射血分数均降低（11 - 39%）。该研究表明，二维超声心动图是一种有用的非侵入性床边技术，可提供与左心室局部收缩异常相关的详细定量信息。
