Karchev T, Kabakchiev P
Int J Pediatr Otorhinolaryngol. 1982 Jun;4(2):149-56. doi: 10.1016/0165-5876(82)90090-8.
Twenty tonsils from children aged 3-6 years removed by operation due to recurrent tonsillitis have been examined. Electron-microscope observations of the epithelial layer have shown a lowering of the number and a reduction of the tubulo-vesicular system of the M-cells. The squamous stratified epithelium is predominating; it is keratinized in some places. Lymphocytes in an active phase and vascular activity in the parenchyma of the removed tonsils are very rare to observe; these were seen only in relation with the M-cells. The above-mentioned data may serve to prove Surjan Jr.'s 1980 hypothesis on the key-importance of metaplastic change of the tonsillar epithelium in recurrent tonsillitis pathogenesis.
对20个因复发性扁桃体炎而接受手术切除的3至6岁儿童的扁桃体进行了检查。对上皮层的电子显微镜观察显示，M细胞的数量减少，其微管泡系统也有所减少。鳞状复层上皮占主导地位，在某些部位出现角化。在切除的扁桃体实质中，处于活跃期的淋巴细胞和血管活动非常罕见，仅在与M细胞相关的情况下才能看到。上述数据可能有助于证明苏尔扬（Surjan）1980年提出的关于扁桃体上皮化生改变在复发性扁桃体炎发病机制中关键重要性的假说。
