Dehl R E
J Biomed Mater Res. 1982 Sep;16(5):715-9. doi: 10.1002/jbm.820160517.
Questions have been raised about the use of mercury intrusion porosimetry to measure interconnecting pore sizes and void volumes in relatively soft and flexible materials such as porous implant composites of PTFE and carbon fibers. We have studied the effect of precompression of one such commercial composite on the mercury intrusion curves which cover all pore diameters greater than about 16 microns, the range of interest for tissue ingrowth applications. Prior compression by a pressure 20% greater than that encountered by the material during a mercury intrusion experiment did not change the ensuing pore size distribution curve, as compared with a noncompressed sample. Deformation of the material at higher pressures sufficient to decrease the sample volume inelastically by 17, 33, and 67% changed the shape of the mercury intrusion curves significantly, indicating that this technique can be used to detect prior deformation of an "unknown" sample. In the undeformed material, less than 15% of the total void as measured by mercury porosimetry consists of interconnecting pores greater than 100 microns in diameter and more than 50% of the void volume is composed of pores less than 40 microns in diameter.
对于使用压汞法测量相对柔软且灵活的材料（如聚四氟乙烯和碳纤维的多孔植入复合材料）中的连通孔径和孔隙体积，人们提出了一些疑问。我们研究了一种此类商业复合材料的预压缩对汞侵入曲线的影响，这些曲线涵盖了所有大于约16微米的孔径，这是组织向内生长应用所关注的范围。与未压缩样品相比，在比汞侵入实验中材料所承受压力大20%的压力下进行预压缩，并不会改变随后的孔径分布曲线。在足以使样品体积非弹性减小17%、33%和67%的更高压力下材料发生变形，会显著改变汞侵入曲线的形状，这表明该技术可用于检测“未知”样品的先前变形。在未变形材料中，通过压汞法测量的总孔隙中，直径大于100微米的连通孔隙占比不到15%，孔隙体积的50%以上由直径小于40微米的孔隙组成。
