Acute cerebral demyelination: clinical and pathological correlation with computed tomography.

A 30-year-old woman died eleven weeks after the onset of an acute illness during which she developed quadriplegia, dysphasia, incontinence, confusion, emotional lability and gaze palsies. The CT scan demonstrated large white matter low attenuation lesions with no mass effect and minimal contrast enhancement. At necropsy the lesions were shown to be those of massive cerebral demyelination.