表皮：新生大鼠皮肤中药物代谢的一个部位。细胞色素P - 450含量及混合功能氧化酶和环氧化物水解酶活性的研究。 - Suppr

Suppr

超能文献

Epidermis: a site of drug metabolism in neonatal rat skin. Studies on cytochrome P-450 content and mixed-function oxidase and epoxide hydrolase activity.

作者信息

Bickers D R, Dutta-Choudhury T, Mukhtar H

出版信息

Mol Pharmacol. 1982 Jan;21(1):239-47.

PMID:7132961

Abstract

摘要

相似文献

Epidermis: a site of drug metabolism in neonatal rat skin. Studies on cytochrome P-450 content and mixed-function oxidase and epoxide hydrolase activity.

Mol Pharmacol. 1982 Jan;21(1):239-47.

Studies on microsomal cytochrome P-450, monooxygenases and epoxide hydrolase in cultured keratinocytes and intact epidermis from BALB/C mice.

J Pharmacol Exp Ther. 1982 Oct;223(1):163-8.

Drug metabolism in skin. Comparative activity of the mixed-function oxidases, epoxide hydratase, and glutathione S-transferase in liver and skin of the neonatal rat.

Drug Metab Dispos. 1981 Jul-Aug;9(4):311-4.

Fetal and neonatal development of the microsomal monooxygenase system.

Drug Metab Rev. 1976;5(1):1-42.

Xenobiotic metabolizing enzymes are not restricted to parenchymal cells in rat liver.

Mol Pharmacol. 1987 Oct;32(4):463-70.

Comparison of the effects of phenobarbital and its hydroxylated metabolites on drug-metabolizing enzymes during ontogenesis.

Pediatr Pharmacol (New York). 1981;1(4):331-40.

Effect of protein deficiency on the hepatic microsomal mixed function oxidase. III-Influence on aflatoxin B1 metabolism and epoxide hydrase activity.

Biochem Exp Biol. 1978;14(1):45-53.

[Changes in hepatic enzyme activities of drug metabolism in rats exposed to normobaric oxygen].

C R Acad Sci III. 1986;302(20):687-9.

Evidence that coal tar is a mixed inducer of microsomal drug-metabolizing enzymes.

Toxicol Lett. 1982 May;11(3-4):221-7. doi: 10.1016/0378-4274(82)90153-9.

Cytochrome P-450-mediated covalent binding of hexachlorophene to rat tissue proteins.

Mol Pharmacol. 1978 Mar;14(2):323-6.

引用本文的文献

Topical delivery of a naproxen-dithranol co-drug: in vitro skin penetration, permeation, and staining.

Pharm Res. 2010 Dec;27(12):2734-42. doi: 10.1007/s11095-010-0274-8. Epub 2010 Sep 25.

Effect of topical application of clotrimazole to rats on epidermal and hepatic monooxygenase activities and cytochrome P-450.

Arch Dermatol Res. 1989;281(3):198-202. doi: 10.1007/BF00456393.

Modulation of constitutive cytochrome P-450 expression in vivo and in vitro in murine keratinocytes as a function of differentiation and extracellular Ca2+ concentration.

Proc Natl Acad Sci U S A. 1990 Mar;87(5):1825-9. doi: 10.1073/pnas.87.5.1825.

The cytochrome P450 gene superfamily.

Int J Exp Pathol. 1991 Jun;72(3):349-63.

Percutaneous absorption and metabolism of aldrin by rat skin in diffusion cells.

Arch Toxicol. 1991;65(7):599-602. doi: 10.1007/BF01973723.

Biochemical responses of skin to allergenic and non-allergenic nitrohalobenzenes. Evidence that an NADPH-dependent reductase in skin may act as a prohapten-activating enzyme.

Arch Dermatol Res. 1992;284(7):400-8. doi: 10.1007/BF00372070.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验