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持续照射的小鼠细胞中存在的染色体畸变

Chromosome aberration persisting in cells of continuously irradiated mice.

作者信息

Kalina I, Brezáni P, Ondrusseková A, Zahumenská L

出版信息

Neoplasma. 1982;29(4):417-20.

PMID:7133233
Abstract

Cytogenetical analysis of the bone marrow cells in mice irradiated continuously with the dose rate 0.478 Gy/day made within the course of various accumulated doses demonstrated the decrease in the number of chromosome aberrations till the post irradiation day 3 in all groups reaching about 75% on average. At further examination periods on day 10 and 30 the decrease in the aberrations appeared to be slower and was dependent on the magnitude of the accumulated dose. Increased number of the aberrant cells as compared with the controls was noted in the groups with the accumulated dose higher than 10 Gy and on the hundred postirradiation day, as well.

摘要

对以0.478 Gy/天的剂量率持续照射的小鼠骨髓细胞进行的细胞遗传学分析表明,在不同累积剂量过程中,所有组在照射后第3天前染色体畸变数量均减少,平均减少约75%。在照射后第10天和第30天的进一步检查期间,畸变减少似乎较慢,且取决于累积剂量的大小。累积剂量高于10 Gy的组以及照射后第100天,与对照组相比,异常细胞数量增加。

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