Aubert M, Gordeff A, Barrie J, Sarrazin R, Dyon J F, Brambilla C, Parent B, Coulomb M
Poumon Coeur. 1982 May-Jun;38(3):167-75.
Two cases of hypoglycemiant pleural fibroma are reported: -- the first case, in a patient with sarcoidosis, was diagnosed following the onset of neuropsychic manifestations due to hypoglycemia; --the second case, much more atypical, was a patient with an enormous pleural tumor affecting cardiorespiratory function to such a degree that almost total incapacity ensued: the hypoglycemia was detected during routine pre-operative investigations. Various extrathoracic manifestations accompany these tumors: osteo-articular (present in 1 patient), and thyroidal (present in both cases). The various mechanisms proposed to explain the development of hypoglycemia in patients with certain extra-pancreatic tumors are reviewed.
第一例患者患有结节病,因低血糖引发神经精神症状后得以确诊;第二例则更为非典型,患者患有巨大胸膜肿瘤,对心肺功能影响极大,几乎导致完全丧失活动能力,低血糖是在术前常规检查中发现的。这些肿瘤伴有各种胸外表现:骨关节炎(1例患者出现)和甲状腺异常(两例均出现)。本文综述了为解释某些胰腺外肿瘤患者发生低血糖的各种机制。