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氟哌噻吨(“三氟噻吨”)在治疗情绪障碍及精神错乱儿童行为紊乱中的应用。

The use of flupenthixol ('Fluanxol') in the management of behavioural disorders in disturbed and psychotic children.

作者信息

de Coninck G, Denis A

出版信息

Pharmatherapeutica. 1982;3(3):209-14.

PMID:7134229
Abstract

Twenty-four children treated wih flupenthixol for behavioural disorders were studied in the out-patient clinic. The drug was given in small doses (0.4 to 2.0 mg per day) for periods ranging from 6 months to 2 years as an alternative to psychotherapy in cases where the latter was not possible. All patients were diagnosed clinically and psychologically as suffering from progressive symptoms of aggression or psychosis. Both the clinical and the psychological assessments showed improvement, particularly in insomnia and aggression. There was also improvement in social contact and concentration leading to improvement in performance at school. Although the health of the children remained very delicate, the results achieved with flupenthixol appeared to be stable even after treatment was stopped.

摘要

在门诊对24名接受氟哌噻吨治疗行为障碍的儿童进行了研究。该药以小剂量(每天0.4至2.0毫克)给药,疗程为6个月至2年,用于无法进行心理治疗的病例作为替代方法。所有患者经临床和心理诊断均患有进行性攻击症状或精神病症状。临床和心理评估均显示有改善,尤其是在失眠和攻击行为方面。社交接触和注意力也有所改善,从而使学习成绩提高。尽管这些儿童的健康状况仍然很脆弱,但即使在停药后,氟哌噻吨取得的效果似乎仍很稳定。

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