Contamin F, Hauw J J, Singer B, Josset P, Bianco C, Mignot B, Tran Dinh Y, Metzger J
Rev Neurol (Paris). 1982;138(4):337-43.
A 54 year old man without pathologic past history but mild hypertension, obesity and gastric ulcer, presented with a syndrome of Wallenberg. He had complained for five days of progressive and diffuse headache. The neurological condition improved initially, but the patient died suddenly two weeks later. Pathological examination showed no significant alteration except for left ventricular enlargement and mild arteriosclerosis. There was a hemodissection (dissecting aneurysm) of the left vertebral artery next to the inferior oliva. It induced a lateral infarct and a limited dorsal infarct at the middle third level of medulla oblongata. Although the location of the arterial changes is usual, their nature is exceptional. The cause of the arterial hemodissection could not be ascertained: fibrous arterial dysplasia, atherosclerosis or congenital abnormalities of internal elastic layer may be discussed. But no definite conclusion can be reached.
一名54岁男性,无既往病史,但有轻度高血压、肥胖症和胃溃疡,出现了延髓背外侧综合征。他主诉渐进性弥漫性头痛已五天。神经系统状况最初有所改善,但患者两周后突然死亡。病理检查显示除左心室增大和轻度动脉硬化外无明显改变。在橄榄下侧紧邻处有左椎动脉壁间剥离(夹层动脉瘤)。它导致延髓中三分之一水平处的外侧梗死和局限性背侧梗死。尽管动脉病变的位置常见,但其性质罕见。动脉壁间剥离的原因无法确定:可能会讨论纤维肌性发育不良、动脉粥样硬化或内弹性层先天性异常。但无法得出明确结论。