Yonekura M, Austin G, Hayward W
Surg Neurol. 1982 Aug;18(2):123-30. doi: 10.1016/0090-3019(82)90371-8.
A group of 107 consecutive patients with patent extracranial-intracranial bypasses were followed an average of 25.2 months to determine the long-term results on regional cerebral blood flow (rCBF), transient ischemic attacks (TIAs), and stroke incidence. Average mean rCBF initially rose to 110% at 1 week, then gradually fell to 105% at 6 months, and 85% at 2 years. Maximum increase in cerebral blood flow occurred in patients with middle cerebral artery stenosis or those in the preoperative low flow group, i.e., less than 50 ml/100 gm/min. In the group with TIAs plus mild stroke, the mean rCBF rose to 122% at 1 week, compared to the group with TIAs only who showed a mean increase to 107% at one week. Clinical improvement was excellent or good in 82% of those with TIAs only; in those with TIAs plus mild stroke, 77% had excellent or good relief of TIAs; and in those with mild stroke only, 70% recovered from their neurological deficits. In the 25.2 months of average follow-up, stroke occurred in only 1 patient on the side of the anastomosis, and in 2 patients on the side opposite the anastomosis, giving an average stroke incidence of 1.5% per year.
对107例连续的颅外-颅内搭桥通畅的患者进行了平均25.2个月的随访，以确定区域脑血流量（rCBF）、短暂性脑缺血发作（TIA）和中风发生率的长期结果。平均rCBF最初在1周时升至110%，然后在6个月时逐渐降至105%，在2年时降至85%。脑血流量的最大增加发生在大脑中动脉狭窄的患者或术前低流量组的患者中，即低于50 ml/100 gm/min。在有TIA加轻度中风的组中，平均rCBF在1周时升至122%，而仅患有TIA的组在1周时平均增加至107%。仅患有TIA的患者中82%的临床改善为优秀或良好；在患有TIA加轻度中风的患者中，77%的TIA得到了优秀或良好的缓解；仅患有轻度中风的患者中，70%从神经功能缺损中恢复。在平均25.2个月的随访中，仅1例患者在吻合侧发生中风，2例患者在吻合对侧发生中风，每年的平均中风发生率为1.5%。
