Holstein P
Acta Orthop Scand. 1982 Oct;53(5):821-31. doi: 10.3109/17453678208992300.
In 102 leg amputations for arterial occlusion including 84 below-knee (BK), 16 above-knee (AD) and 2 through-knee (TK) amputations, the amputation level was determined by means of clinical criteria. The healing results and the selection of levels were then compared with sealed preoperative measurements of the skin perfusion pressure (SPP). Out of 62 BK amputations with an SPP above 30 mmHg wound healing failed in only 2 cases (3 per cent). Out of 13 BK amputations with an SPP between 20 and 30 mmHg 7 cases (54 per cent) failed and out of 9 BK amputations with an SPP below 20 mmHg no less than 8 cases (89 per cent) failed to heal. The difference in failure rate is significant (P less than 0.0001). Out of the 15 failed BK amputations at low pressures (below 30 mmHg) only one case had local signs of ischaemia, which might have warned the surgeons. On the other hand, in 13 out of the 18 cases of primary AK (or TK) amputations there were clinical signs of ischaemia of the calf, comprising temperature demarcation, cyanosis and/or necrotic skin lesion. The SPP below the knee appeared in all these cases to lie below 30 mmHg. In the 5 other cases of primary AK (or TK) amputation the knee was sacrificed for reasons other than signs of local ischaemia, e.g. poor physical or mental condition. It was moreover found that the presence of pulsations in the popliteal artery indicated an 89 per cent chance of healing of BK amputations. Infection was present in 24 BK amputations (28 per cent) and equally frequent among diabetic and non-diabetic cases. The postoperative SPP measured on the stumps averaged only 5 mmHg (P less than 0.05) higher than the preoperative SPP explaining why the preoperative SPP related closely to the postoperative course. It is concluded that ischaemia at the BK election site cannot be ruled out by clinical assessment alone and that preoperative determination of the SPP can be used in determining the chance of healing in BK amputations.
在102例因动脉闭塞而进行的截肢手术中,包括84例膝下截肢(BK)、16例膝上截肢(AK)和2例膝部贯通截肢(TK),截肢平面通过临床标准确定。然后将愈合结果和截肢平面的选择与术前密封测量的皮肤灌注压(SPP)进行比较。在62例SPP高于30 mmHg的BK截肢中,仅有2例(3%)伤口愈合失败。在13例SPP介于20至30 mmHg之间的BK截肢中,7例(54%)愈合失败,而在9例SPP低于20 mmHg的BK截肢中,多达8例(89%)未能愈合。失败率的差异具有显著性(P小于0.0001)。在15例低压力(低于30 mmHg)下失败的BK截肢中,只有1例有局部缺血迹象,这本可警示外科医生。另一方面,在18例一期AK(或TK)截肢病例中,有13例存在小腿缺血的临床体征,包括温度分界、发绀和/或坏死性皮肤病变。在所有这些病例中,膝下SPP似乎都低于30 mmHg。在另外5例一期AK(或TK)截肢病例中,截肢是由于局部缺血迹象以外的原因,如身体或精神状况不佳。此外还发现,腘动脉有搏动表明BK截肢愈合的几率为89%。24例BK截肢(28%)存在感染,在糖尿病和非糖尿病病例中感染频率相同。残肢上术后测量的SPP平均仅比术前SPP高5 mmHg(P小于0.05),这解释了术前SPP与术后病程密切相关的原因。结论是,仅通过临床评估不能排除BK截肢部位的缺血情况,术前测定SPP可用于确定BK截肢的愈合几率。