Møller B N, Sølund K, Hansen S L
Arch Orthop Trauma Surg (1978). 1985;104(4):262-4. doi: 10.1007/BF00450221.
The importance of postoperative wound infection in major amputations was elucidated by recording the organisms isolated in preoperatively infected gangrene and in postoperatively infected wounds of patients undergoing lower-limb amputations for ischemia. Sixty-four amputations were performed on 61 patients. The frequency of coexisting diabetes mellitus was 34%. Postoperative infections occurred in nearly two-thirds of the 19 cases of infected gangrene, as compared with less than one-third of cases of noninfected gangrene. The presence of diabetes mellitus did not significantly influence the infection rate. Preoperatively as well as postoperatively, the most frequently isolated bacterium was Staphylococcus aureus. Clostridium perfringens was cultured in four cases. Postoperative wound infection following lower-limb amputation for ischemia is the main reason for reamputation, especially in patients with infected gangrene.
通过记录因缺血接受下肢截肢手术患者术前感染性坏疽和术后感染伤口中分离出的微生物，阐明了大截肢术后伤口感染的重要性。对61例患者进行了64次截肢手术。并存糖尿病的发生率为34%。19例感染性坏疽患者中近三分之二发生了术后感染，相比之下，非感染性坏疽患者中不到三分之一发生了术后感染。糖尿病的存在对感染率没有显著影响。术前和术后，最常分离出的细菌是金黄色葡萄球菌。4例培养出产气荚膜梭菌。因缺血进行下肢截肢术后的伤口感染是再次截肢的主要原因，尤其是在感染性坏疽患者中。
