Hosler J P, Kimmel K K, Moeller D D
Am J Gastroenterol. 1982 Nov;77(11):854-5.
Brownish discoloration of the muscular layers of the small intestine has been described in association with deficiency of fat soluble vitamin E occurring in various disorders with malabsorption. A patient presenting with diarrhea ultimately found to have "brown bowel syndrome" is reported with serum levels of vitamin E before and during treatment. A brief review of the nature and significance of ceroid pigmentation of the intestine is included; however, the pathophysiology of the brown bowel syndrome remains to be fully elucidated.
小肠肌层的褐色变色已被描述为与各种吸收不良疾病中发生的脂溶性维生素E缺乏有关。本文报告了一名最终被诊断为“褐色肠综合征”的腹泻患者治疗前后的血清维生素E水平。文中还简要回顾了肠道类脂色素沉着的性质和意义；然而，褐色肠综合征的病理生理学仍有待充分阐明。
