Arem R, Jeang M K, Blevens T C, Waddell C C, Field J B
Arch Intern Med. 1982 Nov;142(12):2199-201.
A patient with polycythemia rubra vera had had a leukocyte count between 55,000 and 86,000/cu mm and had had serum glucose levels as low as 8 mg/dL. Despite these low serum glucose values, the patient was asymptomatic, and a more careful investigation disclosed that the hypoglycemia was artifactual. This phenomenon, reported in other leukemic states, to our knowledge, has not been previously described in patients with polycythemia rubra vera. Our case broadens the spectrum of the causes of artifactual low serum glucose concentration due to excessive glucose consumption by the WBCs. This phenomenon is related to extreme leukocytosis, regardless of the underlying disease. Unnecessary workup for hypoglycemia can be avoided if its artifactual nature is suspected in any patient with a reported low serum glucose level and high WBC count.
一名真性红细胞增多症患者的白细胞计数在55,000至86,000/立方毫米之间，血清葡萄糖水平低至8毫克/分升。尽管血清葡萄糖值很低，但该患者并无症状，更仔细的检查发现低血糖是人为造成的。据我们所知，这种现象在其他白血病状态中已有报道，但此前在真性红细胞增多症患者中尚未见描述。我们的病例拓宽了因白细胞过度消耗葡萄糖导致人为性低血清葡萄糖浓度的病因范围。这种现象与极度白细胞增多有关，与潜在疾病无关。如果在任何报告血清葡萄糖水平低且白细胞计数高的患者中怀疑低血糖具有人为性质，就可以避免进行不必要的低血糖检查。
