Yamada A, Mitsuhashi K, Miyakawa Y, Kosaka K, Takehara K, Iijima M, Tanaka K, Shibata S
Clin Nephrol. 1982 Oct;18(4):211-5.
A 48-year-old male, who had been suffering from eosinophilic lymphfolliculosis of the skin (Kimura's disease) for six years, developed the nephrotic syndrome. Renal biopsy revealed immunopathological and electron microscopic changes characteristic of membranous glomerulonephritis. A review of the literature disclosed a high frequency of renal involvement in Kimura's disease. Out of 175 reported cases of the disease, 21 (12%) were found to have proteinuria including 13 who had the nephrotic syndrome. Some of the patients were noticed to have proteinuria before the onset of the skin lesions, suggesting the existence of common etiological factor(s) capable of inducing both skin and kidney lesions.
一名48岁男性，患皮肤嗜酸性淋巴滤泡增生症（木村病）6年，并发肾病综合征。肾活检显示为膜性肾小球肾炎的免疫病理及电镜特征性改变。文献回顾发现木村病肾脏受累频率较高。在175例已报道的该疾病病例中，发现21例（12%）有蛋白尿，其中13例患有肾病综合征。部分患者在皮肤病变出现之前就已出现蛋白尿，提示存在能同时诱发皮肤和肾脏病变的共同病因。
