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木村病,一份埃塞俄比亚罕见病例报告。

Kimura disease, a rare Ethiopian case report.

作者信息

Molla Yohannis Derbew, Alemu Hirut Tesfahun, Zegeye Kassa Berie, Bekele Tiruzer, Tadesse Amanuel Kassa, Answar Isak Omer

机构信息

Department of Surgery, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

Heliyon. 2024 Oct 22;10(20):e39651. doi: 10.1016/j.heliyon.2024.e39651. eCollection 2024 Oct 30.

Abstract

INTRODUCTION

Kimura disease is a chronic inflammatory disorder predominantly affecting the head and neck region. The etiology of Kimura disease remains unclear. The disease mainly affects young adult males of Asian descent, with a higher prevalence in East Asian countries.

CLINICAL PRESENTATION

a 48-year-old Ethiopian woman presented with swelling in both her lower extremities, which gradually progressed to include her abdomen and the rest of her body. Additionally, she had pain in multiple joints in her upper and lower extremities, high-grade fever, loss of appetite, night sweats, and unexplained weight loss over the same duration. Physical examination revealed swelling around the eyes (periorbital puffiness), enlarged nodes in the axillary, and inguinal areas on both sides of the body, and pitting edema. Investigations showed pneumonia, elevated renal function tests and kimura disease. Unfortunately, the patient signed medical advice before completing her management.

CONCLUSION

despite its rarity in Ethiopia, it is imperative to consider Kimura disease as a potential diagnosis when evaluating lymphadenopathy and renal derangement.

摘要

引言

木村病是一种主要影响头颈部区域的慢性炎症性疾病。木村病的病因尚不清楚。该疾病主要影响亚洲血统的年轻成年男性,在东亚国家发病率较高。

临床表现

一名48岁的埃塞俄比亚女性出现双下肢肿胀,逐渐发展至腹部及身体其他部位。此外,在同一时期,她还出现了上下肢多个关节疼痛、高热、食欲不振、盗汗以及不明原因的体重减轻。体格检查发现眼部周围肿胀(眶周水肿)、双侧腋窝及腹股沟区淋巴结肿大以及凹陷性水肿。检查显示患有肺炎、肾功能检查指标升高以及木村病。不幸的是,患者在完成治疗前签署了医嘱。

结论

尽管木村病在埃塞俄比亚较为罕见,但在评估淋巴结病和肾脏紊乱时,必须将其视为一种可能的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9f1/11538783/3ad77c02f3d3/gr1.jpg

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