Zouchová Z, Nerud F, Musílek V
Folia Microbiol (Praha). 1982;27(4):237-41. doi: 10.1007/BF02877122.
Addition of L-tryptophan to cultures of the basidiomycete Oudemansiella mucida brought about a pronounced increase of production of the antibiotic mucidin. The highest increase was reached in the presence of 0.15-0.20% tryptophan and after its addition to a l-d culture. The methyl ester of tryptophan exhibited the same effect. Mycelium growing during the initial phases in the presence of tryptophan synthesized mucidin powerfully during later phases of the fermentation.
向担子菌黏奥德蘑的培养物中添加L-色氨酸可显著提高抗生素黏菌素的产量。在添加0.15 - 0.20%色氨酸并将其添加到对数期培养物后,产量达到最高增长。色氨酸甲酯也表现出相同的效果。在发酵前期于色氨酸存在下生长的菌丝体,在发酵后期能大量合成黏菌素。