Baenkler H W
Fortschr Med. 1982 Sep 23;100(36):1647-50.
Vasculitis due to immunological mechanisms is caused by attachment of immune-complexes to the wall of vessels. This occurs in capillaries causing dysfunction and damage or organs or in other vessels causing isolated vasculitis. Regularly, also serositis can be seen. Best known examples are systemic lupus erythematosus and serum-sickness. Diagnosis refers to the detection of antigen and antibody or of immune-complexes. Steroids and antiinflammatory as well as immunosuppressive drugs are used for therapy. During the acute phase also plasmapheresis is of benefit.
免疫机制导致的血管炎是由免疫复合物附着于血管壁引起的。这发生在毛细血管中,导致功能障碍和器官损伤,或发生在其他血管中,导致孤立性血管炎。通常也可见浆膜炎。最著名的例子是系统性红斑狼疮和血清病。诊断是指检测抗原、抗体或免疫复合物。治疗使用类固醇、抗炎药和免疫抑制药物。在急性期,血浆置换也有益处。