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原发性心脏黏液肉瘤脑转移——1例报告(作者译)

[Brain metastases from primary cardiac myxosarcoma--report of a case (author's transl)].

作者信息

Kayama T, Hori S

出版信息

No Shinkei Geka. 1978 Sep;6(9):925-30.

PMID:714243
Abstract

A very rare case of a myxosarcoma with metastases to the brain is reported. A 33-year-old female was admitted to our hospital because of lassitude, fever, slight left hemiparesis, headache and other signs of intracranial hypertension and cardiac symptoms such as dyspnea and palpitation. She had the cardiac symptoms once 14 years before, which reappeared and rapidly aggravated two months before the admission. Cerebral angiography revealed a mass in the right temporal lobe and physical and laboratory examinations revealed mitral value failure and hyperthyroidism. On the next day, March 19, 1976, a grossly cystic 60 gm tumor was totally removed which was largely imbedded in the subcortex of the right temporal lobe. The symptoms except for the cardiac symptoms and disseminated intravascular coagulopathy rapidly improved, but headache and left hemiparesis returned 13 days postoperatively. She died suddenly 18 days after the operation due to acute cardiac failure. Autopsy revealed two separate hard and solid tumors both attached to the mitral valve and occupied the whole left atrium and another metastasis to the frontal lobe which had not been diagnosed before the death. Microscopic examinations including electronmicroscopic study established the diagnosis of myxosarcoma in all the four tumors.

摘要

报告了一例极为罕见的黏液肉瘤脑转移病例。一名33岁女性因疲倦、发热、轻度左侧偏瘫、头痛及其他颅内高压症状和如呼吸困难、心悸等心脏症状入住我院。她14年前曾出现过心脏症状,此次入院前两个月再次出现且迅速加重。脑血管造影显示右侧颞叶有一肿块,体格检查和实验室检查显示二尖瓣功能衰竭和甲状腺功能亢进。1976年3月19日次日,一个大体呈囊性、重60克的肿瘤被完整切除,该肿瘤大部分嵌入右侧颞叶皮质下。除心脏症状和弥散性血管内凝血外,其他症状迅速改善,但术后13天头痛和左侧偏瘫又复发。术后18天,她因急性心力衰竭突然死亡。尸检发现两个独立的硬实性肿瘤均附着于二尖瓣并占据整个左心房,另一个转移至额叶,生前未被诊断出。包括电子显微镜研究在内的显微镜检查确诊所有四个肿瘤均为黏液肉瘤。

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