Kumakiri M, Takashima I, Iju M, Nogawa M, Miura Y
J Am Acad Dermatol. 1982 Oct;7(4):461-7. doi: 10.1016/s0190-9622(82)70127-6.
A 29-year-old man and a 29-year-old woman developed over fifty asymptomatic, slate-colored macules disseminated mainly on the forehead. Histologic study revealed keratinous cysts in the dermis, lined by a few layers of epithelial cells with rudimentary hair bulb-like structures. The cysts' contents were vellus hair fragments and laminated horny material. Ultrastructural studies of the second case disclosed that the keratinization of the cyst wall was similar to that of the infundibular portion of the outer root sheath. It is suggested that our two cases are a type of follicular hamartoma. Similar follicular hamartomas, eruptive vellus hair cysts have been reported previously. The cysts were located in the chest and/or extremities and had a tendency to be eliminated transepidermally. Although these clinical features were different from ours, the characteristic histologic features were the same; therefore, our cases might be a variant of eruptive vellus hair cysts.
一名29岁男性和一名29岁女性前额出现了五十多个无症状的石板色斑疹，主要散布于前额。组织学研究显示真皮内有角质囊肿，内衬几层上皮细胞，伴有原始的毛球样结构。囊肿内容物为毳毛碎片和板层状角质物质。第二例的超微结构研究表明，囊肿壁的角化与外根鞘漏斗部相似。提示我们的这两例病例属于毛囊错构瘤的一种类型。之前曾报道过类似的毛囊错构瘤，即发疹性毳毛囊肿。这些囊肿位于胸部和/或四肢，有经表皮排出的倾向。虽然这些临床特征与我们的病例不同，但其特征性组织学特征相同；因此，我们的病例可能是发疹性毳毛囊肿的一种变体。
