Dalens B, Bezou M J, Travade P, Vanneuville G, Haberer J P, Coulet M
J Gynecol Obstet Biol Reprod (Paris). 1982;11(4):483-6.
The authors report the results of a prospective test of NBT carried out by an original method already described, and now used for seventy newborn babies. Eleven of them (group I) were tested by simultaneously taken samples from the cord and the heel in the labour ward. The levels obtained according to the position from which the samples were taken showen no significant difference. In 59 other infants (group 2) three successive tests were carried out in the first two weeks of life. These results were classified according to whether the children were: infected, perhaps infected and non-infected. The results confirm correlations between raised levels and infections. Giving antibiotic therapy does not alter significantly the levels in non-infected babies, nor the high positive scores in infected babies that were revealed in the four days after the start of treatment. Following this delay, levels of infected babies' blood did drop significantly, which was a probable indication of the efficacy of the antibiotic therapy.
作者报告了一项通过已描述的原始方法对硝基蓝四氮唑（NBT）进行的前瞻性测试结果，该方法现用于70名新生儿。其中11名（第一组）在产房同时采集脐带血和足跟血进行检测。根据采血部位获得的水平显示无显著差异。另外59名婴儿（第二组）在出生后的前两周内进行了三次连续检测。这些结果根据儿童是否感染、可能感染和未感染进行分类。结果证实了水平升高与感染之间的相关性。给予抗生素治疗对未感染婴儿的水平没有显著影响，对治疗开始后四天内感染婴儿出现的高阳性评分也没有显著影响。在此延迟之后，感染婴儿的血液水平确实显著下降，这可能表明抗生素治疗有效。
