[Angioimmunoblastic lymphadenopathy with dysproteinemia. Clinical case report].

The clinico-histologico-biological picture of a recently identified haematological condition distinguished by marked superficial generalized adenomegaly, a typical lymph node biopsy report (lively immunoblastic and angioblastic proliferation, deposits of PAS-positive eosinophil homogenous material) and hypergammaglobulinaemia (polyclonal gammopathy) and defined as angio-immunoblastic lymphadenopathy with dysproteinaemia, is described. On the basis of numerous reported cases and the clinical case in question, the pathogenetic interpretation whereby the condition is considered as a reaction in similar fashion to what is already known for the so-called GvHr (transplant to host reaction), independently of the as yet unknown and perhaps many-sided aetiological factor, is upheld. The condition is substantially benign, although the possibility that it will become malignant cannot be excluded. It is highly sensitive to radiant, cytostatic and cortiocosteroid therapy although there are profound prognostic reservations about its great susceptibility to infections, particularly at respiratory level.