[Pharmacokinetic and clinical research on a new aminoglycoside antibiotic: sisomicin].
作者信息
Di Nola F, Soranzo M L, Bosio G, Sachelariu N, Guasco C, Bendiscioli L, Bisarello I
出版信息
Minerva Med. 1978 Sep 19;69(43):2951-62.
PMID:714275
Abstract
Results obtained with sisomycin in 10 cases of purulent meningitis and 4 of bronchopulmonitis showed good tissue diffusion, together with CSF concentrations sufficient to inhibit the main aetiological agents in these forms: MIC 0.02 mg/ml for both D. pneumoniae (I-ATCC 6301) and N. meningitidis (C-ATCC 13101), i.e. liquor transfer of the antibiotic more than sufficient to handle these agents.
摘要
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