Sabbah H N, Stein P D, Hawkins E T, Viano D C, Vostal J J
J Trauma. 1982 Nov;22(11):937-43. doi: 10.1097/00005373-198211000-00009.
The purpose of this study was to explore the possibility of extrinsic coronary artery compression following nonpenetrating cardiac trauma. Direct impact on the anterior surface of the heart was produced by a blunt air-pressurized impactor in 34 open-chest anesthetized dogs. Sections from the left anterior descending coronary artery and the left circumflex coronary artery were obtained for microscopic examination from each of the 17 dogs that survived the duration of observation (90 minutes). Gross examination of the external surface of the heart showed contusions over the anterior surface and prominent extravascular hemorrhage that followed the course of the left anterior descending coronary artery, showed no contusion or extravascular bleeding. In most instances, light microscopy showed narrowing of the lumen of the left anterior descending coronary artery with concave deformation resulting from compression by blood around the vessel. The cross-sections of the circumflex coronary artery, although sometimes oblong, showed no concave deformation. These observations suggest that extrinsic compression of the coronary artery may cause coronary narrowing following nonpenetrating cardiac trauma.
本研究的目的是探讨非穿透性心脏创伤后冠状动脉受到外部压迫的可能性。在34只开胸麻醉犬中，使用钝性气压冲击器直接撞击心脏前表面。从观察期（90分钟）内存活的17只犬中，获取左前降支冠状动脉和左旋支冠状动脉的切片进行显微镜检查。心脏外表面的大体检查显示，前表面有挫伤，沿左前降支冠状动脉走行有明显的血管外出血，左旋支冠状动脉未见挫伤或血管外出血。在大多数情况下，光学显微镜显示左前降支冠状动脉管腔狭窄，因血管周围血液压迫导致管腔呈凹形变形。左旋支冠状动脉的横截面虽然有时呈椭圆形，但未显示凹形变形。这些观察结果表明，非穿透性心脏创伤后冠状动脉受到外部压迫可能会导致冠状动脉狭窄。
