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甲苯咪唑糊剂作为驱虫药在随机来源研究猫中的应用

Mebendazole paste as an anthelmintic in random source research cats.

作者信息

Bradley R E, Peters L J

出版信息

Lab Anim Sci. 1982 Oct;32(5):523-4.

PMID:7144129
Abstract

Mebendazole paste, administered per os daily for 3 days, at dose levels of 22 mg/kg and 33 mg/kg was highly effective in removing Ancylostoma tubaeforme from naturally infected cats. The 22 mg/kg dose gave the highest efficacy (95.5% critical and 98% controlled). The same product at 11 mg/kg, 22 mg/kg, or 33 mg/kg was 100% effective in removing Toxocara cati from naturally infected cats. Both 11 mg/kg and 22 mg/kg dose levels were highly efficacious against the common tapeworm, Dipylidium caninum. No toxic side effects or clinical illness were observed in any of the cats used in this study.

摘要

甲苯咪唑膏剂,每日经口给药,连续3天,剂量分别为22毫克/千克和33毫克/千克,对自然感染管形钩口线虫的猫有高效驱虫作用。22毫克/千克剂量组的驱虫效果最佳(临界治愈率95.5%,完全治愈率98%)。同一产品,剂量为11毫克/千克、22毫克/千克或33毫克/千克时,对自然感染猫弓首蛔虫的猫驱虫效果达100%。11毫克/千克和22毫克/千克剂量水平对常见绦虫犬复孔绦虫均有高效驱虫作用。本研究中使用的所有猫均未观察到任何毒副作用或临床疾病。

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