McRae R G, Bellino J P, Khasgiwala C
Laryngoscope. 1982 Nov;92(11):1247-8.
Malignant melanoma of the nasal mucous membrane continues to be a rare disorder which is difficult to treat. Five year survival rate appears to be less than 30% and most patients who die of the disease have distant metastasis. At this time, the otolaryngologist and head and neck surgeons must strive to control local and regional disease with surgical means. Unfortunately, these means are usually inadequate because survival is critically dependent on the biology of the melanoma and its interaction with the patient's immune system.
鼻黏膜恶性黑色素瘤仍然是一种罕见且难以治疗的疾病。五年生存率似乎低于30%，大多数死于该疾病的患者都有远处转移。此时，耳鼻喉科医生和头颈外科医生必须努力通过手术手段控制局部和区域疾病。不幸的是，这些手段通常并不充分，因为生存严重依赖于黑色素瘤的生物学特性及其与患者免疫系统的相互作用。
