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职业性铅接触中的红细胞锌原卟啉浓度

[Erythrocyte zinc protoporphyrin concentration in occupational exposure to lead].

作者信息

Stankiewicz A, Frydrych J

出版信息

Med Pr. 1982;33(1-3):25-30.

PMID:7144540
Abstract

The paper is aimed at analysing the correlation between zinc protoporphyrin and hemoglobin concentrations and lead level in blood and the correlation between hemoglobin concentration and zinc protoporphyrin content in erythrocytes. The studies covered 73 men aged 19-58, exposed for 1-15 years. The control group was composed of 20 healthy men, age interval 17-66, with no occupational exposure to lead. A statistically significant difference for zinc protoporphyrin was demonstrated between the control and examined groups. No significant difference was found in hemoglobin concentration between those groups. On the other hand, a highly statistically significant increase with time was found in zinc protoporphyrin in erythrocytes. The dependence of zinc protoporphyrin concentration on lead concentration increases with employment length, reaching the correlation coefficient 0.6 after more than 9 years. No correlation was found between hemoglobin and lead concentrations in blood. Neither was it found between hemoglobin and zinc protoporphyrin concentrations.

摘要

本文旨在分析锌原卟啉与血红蛋白浓度、血铅水平之间的相关性,以及血红蛋白浓度与红细胞中锌原卟啉含量之间的相关性。研究对象为73名年龄在19至58岁之间、接触铅1至15年的男性。对照组由20名年龄在17至66岁之间、无职业性铅接触的健康男性组成。对照组与检测组之间锌原卟啉存在统计学显著差异。两组之间血红蛋白浓度未发现显著差异。另一方面,红细胞中锌原卟啉随时间呈现高度统计学显著增加。锌原卟啉浓度对铅浓度的依赖性随就业时长增加,超过9年后相关系数达到0.6。血中血红蛋白与铅浓度之间未发现相关性。血红蛋白与锌原卟啉浓度之间也未发现相关性。

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