新重新接触铅的冶炼工人的游离红细胞原卟啉、锌原卟啉和血铅水平：一项前瞻性研究。

Free erythrocyte protoporphyrin, zinc protoporphyrin and blood lead in newly re-exposed smelter workers: a prospective study.

作者信息

Lerner S, Gartside P, Roy B

出版信息

Am Ind Hyg Assoc J. 1982 Jul;43(7):516-9. doi: 10.1080/15298668291410134.

Abstract

The relationship between blood lead and free erythrocyte protoporphyrin (FEP) or zinc protoporphyrin (ZPP) was evaluated prospectively for 50 weeks in a group of workers who were removed from occupational lead exposure for 10 weeks. FEP or ZPP continued to fall in spite of a rising blood lead upon re-exposure. Although statistically significant relationships between square root FEP or ZPP and blood lead were found, wide confidence limits prevent meaningful predictions of blood lead from FEP or ZPP for an individual. Blood lead is a better index of exposure than FEP or ZPP, especially when exposure is not stable.

摘要

对一组脱离职业性铅暴露10周的工人进行了为期50周的前瞻性评估，以研究血铅与游离红细胞原卟啉（FEP）或锌原卟啉（ZPP）之间的关系。重新接触铅后，尽管血铅水平上升，但FEP或ZPP仍持续下降。虽然发现FEP或ZPP的平方根与血铅之间存在统计学上的显著关系，但较宽的置信区间使得无法根据个体的FEP或ZPP对血铅进行有意义的预测。血铅比FEP或ZPP更能准确反映铅暴露情况，尤其是在暴露不稳定时。