Tobolka-Christian G
Padiatr Padol. 1978;13(4):425-8.
4 cases of extrapyramidal disturbances, observed in children with Metoclopramid-medication, are reported. These side-effects may occur already at normal therapeutic dosage, especially in the young patient. The side-effects are reversible, and respond easily to i.v. injection or peroral application of anti-parkinsonian drugs, less severe cases may subside by withdrawal of the drug. The therapeutic use in the pediatric field must be strictly indicated because of the special disposition of children to the side-effects described above.
报告了4例在使用甲氧氯普胺治疗的儿童中观察到的锥体外系障碍病例。这些副作用甚至在正常治疗剂量下就可能出现,尤其是在年轻患者中。副作用是可逆的,静脉注射或口服抗帕金森病药物很容易缓解,症状较轻的病例停药后可能会消退。由于儿童对上述副作用有特殊易感性,在儿科领域的治疗应用必须严格掌握指征。