Vitvitskaia L V, Bikbulatova L S, Vitvitskiĭ V N
Ontogenez. 1982 Sep-Oct;13(5):541-5.
The fractional composition of chromatin proteins of various morphological structures and areas in the rabbit and human brain was studied by means of electrophoresis in polyacrylamide gel with sodium dodecyl sulphate at different stages of pre- and postnatal ontogenesis. Both the species are characterized by differences in the set of chromatin proteins between different brain structures (regional heterogeneity) arising and increasing during ontogenesis. The heterochronism was found in the appearance of a number of high molecular weight fractions of chromatin proteins suggesting the advanced development of genetic apparatus of the phylogenetically ancient brain structures. The human brain, unlike the rabbit one, is characterized by individual differences augmenting during ontogenesis.
采用十二烷基硫酸钠聚丙烯酰胺凝胶电泳法，研究了家兔和人出生前及出生后不同发育阶段大脑中各种形态结构和区域的染色质蛋白的组分比例。这两个物种的特点是，在个体发育过程中，不同脑结构之间染色质蛋白的种类存在差异（区域异质性），且这种差异会出现并增加。在一些高分子量染色质蛋白组分的出现过程中发现了异时性，这表明系统发育古老的脑结构的遗传装置发育提前。与家兔不同，人类大脑的特点是个体差异在个体发育过程中不断增大。
