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[铅中毒检测试验的敏感性和特异性]

[Sensitivity and specificity of lead poisoning detection tests].

作者信息

Dally S, Bensaid A, Buisine A, Thomas G, Fournier E

出版信息

Nouv Presse Med. 1982 Sep 25;11(37):2757-9.

PMID:7145666
Abstract

The results of biochemical tests used for the supervision of factory workers exposed to lead (notably lead serum levels, urinary aminolevulinic acid (ALA) and punctuated red cells) were compared in 90 patients. The reference test used to evaluate the sensitivity and specificity of these examinations was EDTA-induced lead urinary excretion. Lead serum levels and urinary ALA were about equally effective in providing information. However, these two tests were more sensitive when performed simultaneously than when performed separately. It is suggested that both should be requested when trying to prevent lead poisoning.

摘要

对90名接触铅的工厂工人(尤其是血清铅水平、尿氨基乙酰丙酸(ALA)和点彩红细胞)进行生化检测的结果进行了比较。用于评估这些检查敏感性和特异性的参考检测是依地酸(EDTA)诱导的尿铅排泄。血清铅水平和尿ALA在提供信息方面效果大致相同。然而,这两项检测同时进行时比单独进行时更敏感。建议在试图预防铅中毒时同时进行这两项检测。

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