Dangoumau J, Begaud B
Nouv Presse Med. 1982 Oct 14;11(40):2995-7.
By imputability it is meant the assessment of the probable responsability of a drug in the development of undesirable effect. Its principle is based on the evaluation of some criteria derived from observation (intrinsic imputability) or relevant literature (extrinsic imputability). Around ten imputability methods have so far been reported; although they are not comparable, personnel differences in evaluation may be avoided.
可归责性是指对药物在不良反应发生过程中可能的责任进行评估。其原则基于对从观察中得出的一些标准(内在可归责性)或相关文献(外在可归责性)的评估。迄今为止,已报道了大约十种可归责性方法;尽管它们不可比,但可以避免评估中的人员差异。