Horev G, Price R R, Erickson J J, Fleischer A C, James A E
Radiology. 1982 Dec;145(3):773-5. doi: 10.1148/radiology.145.3.7146412.
A prototype computer-augmented diagnostic ultrasound system was used in an investigation of the range of echo amplitudes obtained from measurements of normal exteriorized rat livers. A secondary goal was to develop a method for minimizing variations in measurement techniques and instrument stability. The average echo amplitude was obtained from a user-selected homogeneous region of the liver on a B-mode scan image. A similar B-mode scan of a commercially available liver tissue equivalent phantom was also obtained immediately after each rat liver measurement and was used as a calibration scan. A normalization factor developed from the calibration scan was used to correct all in vivo measurements for system variation. The average echo amplitude from the livers of a group of normal rats, when corrected by the calibration scan, exhibited a narrow range of values with a coefficient of variation of only 5%. The development of a technique that yields a narrow range of values for normal tissues should encourage further investigation of tissue characterization methods.
一种原型计算机辅助诊断超声系统被用于研究从正常体外大鼠肝脏测量中获得的回波振幅范围。第二个目标是开发一种方法，以尽量减少测量技术和仪器稳定性的变化。平均回波振幅是从B模式扫描图像上用户选择的肝脏均匀区域获得的。在每次大鼠肝脏测量后，还立即对市售的肝脏组织等效体模进行了类似的B模式扫描，并将其用作校准扫描。从校准扫描得出的归一化因子用于校正所有体内测量的系统变化。一组正常大鼠肝脏的平均回波振幅经校准扫描校正后，显示出较窄的值范围，变异系数仅为5%。一种能为正常组织产生较窄值范围的技术的发展，应该会鼓励对组织表征方法进行进一步研究。
