Benito M, Lorenzo M, Medina J M
Rev Esp Fisiol. 1982;38 Suppl:237-41.
Foetal rat liver lipogenesis in vivo decreased during the last two days of gestation. Whereas glycogen synthesis of the same tissue had increased between 20-21 days and sharply decreased during the last day. Treatment with dexamethasone increased glycogen synthesis and decreased lipid synthesis at the same time. Conversely, foetal rat lung lipogenesis increased and glycogen synthesis decreased during the last two days of gestation. Treatment with dexamethasone decreased both the rates of lipogenesis and the glycogen synthesis in the same observation period.
妊娠最后两天，胎鼠肝脏的体内脂肪生成减少。而同一组织的糖原合成在20至21天之间增加，并在最后一天急剧下降。地塞米松治疗可同时增加糖原合成并减少脂质合成。相反，在妊娠最后两天，胎鼠肺的脂肪生成增加而糖原合成减少。在相同观察期内，地塞米松治疗降低了脂肪生成率和糖原合成率。
