通过重复呼吸和形态测量技术测定肺组织和毛细血管血容量。

Lung tissue and capillary blood volumes by rebreathing and morphometric techniques.

作者信息

Crapo R O, Crapo J D, Morris A H

出版信息

Respir Physiol. 1982 Aug;49(2):175-86. doi: 10.1016/0034-5687(82)90072-x.

Abstract

Gas rebreathing measurements of lung tissue volume (Vt) and pulmonary capillary blood volume (Vc) were made in five anesthetized dogs. After the rebreathing measurements, the lungs were inflation fixed with glutaraldehyde and analyzed morphometrically. Each lung was morphometrically divided into alveolar and nonalveolar compartments and each compartment was divided into its air, tissue and blood components. Average rebreathing and morphometric measurements of Vc were 42 and 84 ml, respectively. The reasons for this difference remain unclear. The rebreathing Vt (198 ml) was 40 ml (25%) greater than the morphometric alveolar tissue and blood components (158 ml). Assuming that the rebreathing technique measures all of the alveolar compartment, the rebreathing measurement includes a significant fraction of the nonalveolar compartment.

摘要

对五只麻醉犬进行了肺组织容积（Vt）和肺毛细血管血容积（Vc）的气体重吸入测量。在重吸入测量后，用戊二醛对肺进行充气固定并进行形态计量分析。每个肺在形态计量学上被分为肺泡和非肺泡部分，每个部分又被分为空气、组织和血液成分。Vc的平均重吸入测量值和形态计量测量值分别为42毫升和84毫升。这种差异的原因尚不清楚。重吸入Vt（198毫升）比形态计量学上的肺泡组织和血液成分（158毫升）大40毫升（25%）。假设重吸入技术测量了所有肺泡部分，那么重吸入测量包括了相当一部分非肺泡部分。