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抗凝剂-防腐剂枸橼酸盐-磷酸盐-腺嘌呤(CPDA-1)对血液服务的影响。

Impact of the anticoagulant-preservative citrate-phosphate-adenine (CPDA-1) on blood services.

作者信息

McEvoy P M, Kahn R A, Miller W V

出版信息

Transfusion. 1982 Nov-Dec;22(6):532-4. doi: 10.1046/j.1537-2995.1982.22683068621.x.

DOI:10.1046/j.1537-2995.1982.22683068621.x
PMID:7147334
Abstract

The introduction of CPDA-1, as opposed to CPD, has allowed blood banks to store red blood cells for up to 35 days. The Missouri-Illinois Regional Blood Services studied the impact of CPDA-1 in three areas: reduction in blood outdating, change in distribution pattern, and the potential increase in the age of the products transfused. Our eighteen month study showed a reduction in blood outdating from 7.9 per cent to 3.9 per cent. Additionally, each unit of blood was distributed less frequently (from an average of 1.21 to 1.08 times from collection to transfusion). At the same time there was only a small increase in the mean age of the products transfused. It is our conclusion that the benefits of CPDA-1 can be attained with limited impact on the age of the products transfused.

摘要

与CPD相比,CPDA - 1的引入使血库能够将红细胞储存长达35天。密苏里 - 伊利诺伊地区血液服务中心在三个方面研究了CPDA - 1的影响:减少血液过期、改变分配模式以及所输注产品的潜在年龄增加。我们为期18个月的研究表明,血液过期率从7.9%降至3.9%。此外,每单位血液的分配频率降低(从采集到输注的平均次数从1.21次降至1.08次)。与此同时,所输注产品的平均年龄仅有小幅增加。我们的结论是,CPDA - 1的益处能够在对所输注产品的年龄影响有限的情况下实现。

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