一项关于超声多普勒频谱分析检测颈动脉疾病的批判性研究。

A critical study of ultrasound Doppler spectral analysis for detecting carotid disease.

作者信息

Brown P M, Johnston K W, Kassam M, Cobbold R S

出版信息

Ultrasound Med Biol. 1982;8(5):515-23. doi: 10.1016/0301-5629(82)90083-7.

Abstract

The results of in vitro and in vivo studies to determine the application and limitations of frequency analysis for CW Doppler ultrasound assessment of carotid stenoses are reported. In the in vitro study, the peak Doppler frequency and a new spectral broadening index were determined proximal to, at, and distal to axisymmetric and asymmetrical model stenoses. Good correlations with percent area stenoses were found. In the clinical study, 162 cases were examined using a 4 MHz Doppler system and by standard four-vessel arteriography. Peak frequencies of greater than 3.8 KHz were diagnostic of internal carotid stenoses of 3.2 mm minimum lumen diameter or less, with a sensitivity of 92% and a specificity of 94%. Spectral broadening, evaluated by subjective grading, yielded similar results.

摘要

本文报告了体外和体内研究的结果，以确定连续波多普勒超声评估颈动脉狭窄时频率分析的应用及局限性。在体外研究中，测定了轴对称和非对称模型狭窄近端、狭窄处及远端的峰值多普勒频率和一个新的频谱展宽指数。发现其与狭窄面积百分比有良好的相关性。在临床研究中，使用4兆赫多普勒系统和标准的四血管动脉造影术对162例患者进行了检查。峰值频率大于3.8千赫可诊断最小管腔直径为3.2毫米或更小的颈内动脉狭窄，敏感性为92%，特异性为94%。通过主观分级评估的频谱展宽也得出了类似结果。