Trapeznikov N N, Aliev B M, Iur'eva T V
Vopr Onkol. 1982;28(11):20-4.
Radical surgery was performed in 69 cases of primary and recurrent localized soft-tissue sarcomas (extended dissection of tumor--53, exarticulation or amputation--16) after a course of non-uniform irradiation, when other methods of specific treatment had failed. Areas of exposed tumors were irradiated with focal doses of 90-120 Gy, screened areas--with 40-60 Gy. Radiation was delivered through a latticed diaphragm from the same field. Postoperative complications due to intensive irradiation and radiation injury were comparable to those involved in standard radiation procedures. A 5-year survival rate was 50% (primary tumor--16 and relapse--77%).
在69例原发性和复发性局限性软组织肉瘤患者中，当其他特异性治疗方法均告失败后，在进行了一个疗程的不均匀照射后实施了根治性手术（肿瘤扩大切除53例，关节离断或截肢16例）。对暴露的肿瘤区域给予90 - 120 Gy的局部剂量照射，对屏蔽区域给予40 - 60 Gy照射。通过同一野的格子状滤线器进行照射。因强化照射和放射损伤导致的术后并发症与标准放射治疗程序中的并发症相当。5年生存率为50%（原发性肿瘤患者16例，复发患者77例）。
