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[电离辐射与支气管癌]

[Ionizing radiation and bronchial carcinoma].

作者信息

Schüttmann W

出版信息

Z Erkr Atmungsorgane. 1982;159(1):3-15.

PMID:7148031
Abstract

The paper presents a survey of the radiation induced bronchial carcinoma with particular reference to occupational conditions. The central subject is the so-called Schneeberg disease as the most frequent and best studied type of such carcinoma, concerning the aetiology and epidemiology of the disease. After a short historical introduction the importance of the shortliving radon daughters as the actually injurious agents in the underground mines with a radioactive climate is discussed. The evaluation of this type of radiation exposure after inhalation of alpha-emitting radionuclides by means of the measuring quantities working level and working level month is described. From the several publications on the results of epidemiological investigations concerning the incidence of bronchial carcinoma among uranium miners the reports from USA and CSSR are referred to somewhat more in detail. The possibility of a radioactive climate in nonuranium mines and other underground installations is pointed out. Other types of radiation induced bronchial carcinoma are mentioned, emphasizing the character of the Schneeberg disease as a model for all these other kinds. Finally, the possibility to derive risk estimates from the results of epidemiological investigations is demonstrated by means of some selected examples.

摘要

本文介绍了辐射诱发支气管癌的调查情况,特别提及了职业环境。核心主题是所谓的施内贝格病,它是此类癌症中最常见且研究最充分的类型,涉及该病的病因学和流行病学。在简短的历史介绍之后,讨论了短寿命氡子体作为放射性环境下地下矿井中实际致伤因素的重要性。描述了通过测量量工作水平和工作水平月来评估吸入发射α粒子的放射性核素后的这种辐射暴露类型。从关于铀矿工人支气管癌发病率的流行病学调查结果的若干出版物中,对美国和捷克斯洛伐克社会主义共和国的报告提及得稍多一些。指出了非铀矿和其他地下设施中存在放射性环境的可能性。还提到了其他类型的辐射诱发支气管癌,强调施内贝格病作为所有其他类型的模型的特征。最后,通过一些选定的例子展示了从流行病学调查结果得出风险估计的可能性。

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