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尼森-罗塞蒂胃底折叠术治疗胃食管反流

Nissen-Rossetti fundoplication for the treatment of gastro-oesophageal reflux.

作者信息

Matikainen M

出版信息

Acta Chir Scand. 1982;148(2):173-7.

PMID:7148314
Abstract

During 1978 and 1979 20 patients were subjected to fundoplication. All these patients had abnormal oesophageal acid reflux as demonstrated by 18-hour pH-monitoring of the distal oesophagus. They had also complications of this reflux, i.e. oesophageal ulcerations or stricture formation. The patients were reexamined two months postoperatively and 5-22 (mean 13.3) months after operation. The patients' satisfaction was high after operation and the oesophagitis was cured in all. The oesophagus was lengthened from 35.8 +/- S.D. 1.85 cm to 38.7 +/- S.D. 2.25 cm after fundoplication (p less than 0.05) as measured by endoscopy. The mechanism of success of this operation may be related to the return of LES to the intra-abdominal compartment, but also a flutter valve mechanism may be operative.

摘要

在1978年至1979年期间,对20例患者实施了胃底折叠术。通过对食管远端进行18小时的pH监测,所有这些患者均存在异常的食管酸反流。他们还出现了这种反流的并发症,即食管溃疡或狭窄形成。术后两个月以及术后5至22个月(平均13.3个月)对患者进行了复查。术后患者满意度较高,所有患者的食管炎均已治愈。通过内镜检查测量,胃底折叠术后食管长度从35.8±标准差1.85厘米延长至38.7±标准差2.25厘米(p<0.05)。该手术成功的机制可能与下食管括约肌回到腹腔内有关,但也可能存在瓣叶扑动机制。

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The knife or the pill in the long-term treatment of gastroesophageal reflux disease?在胃食管反流病的长期治疗中,选择手术还是药物治疗?
Yale J Biol Med. 1994 May-Aug;67(3-4):233-46.