Buda A J, Dubbin J D, MacDonald I L, Strauss H D, Orr S A, Meindok H
Am J Cardiol. 1982 Dec;50(6):1272-8. doi: 10.1016/0002-9149(82)90462-3.
To examine regional myocardial perfusion after myocardial infarction, 26 patients underwent exercise electrocardiographic testing with thallium-201 myocardial perfusion imaging 3 weeks and 3 months after infarction. At 3 weeks, 9 of 26 patients (35%) had myocardial ischemia by exercise electrocardiographic testing, whereas 18 of 26 (69%) had ischemia by thallium-201 imaging. The thallium-201 scintigrams were scored by dividing each image, in 3 views, into 5 segments, using a 5-point scoring scheme. The exercise thallium-201 score was 44.3 +/- 1.2 and increased to 47.3 +/- 1.2 in the redistribution study (p less than 0.001). Three months after infarction, although there was a significantly greater rate-pressure product which would predict a larger ischemic defect and a decrease in the stress thallium-201 score, the stress score was improved (48.3 +/- 1.1, p less than 0.001). The redistribution score was similar, that is, 48.9 +/- 1.0. The improvement in thallium-201 myocardial perfusion was associated with a loss of stress-induced ischemia in 8 patients (30%). These results indicate that spontaneous improvements in thallium-201 myocardial perfusion imaging may occur after myocardial infarction.
为了检测心肌梗死后局部心肌灌注情况，26例患者在心肌梗死后3周和3个月时接受了运动心电图检查及铊-201心肌灌注显像。在3周时，26例患者中有9例（35%）通过运动心电图检查显示心肌缺血，而26例中有18例（69%）通过铊-201显像显示缺血。铊-201闪烁图通过将每个图像在三个视图中分为5个节段，采用5分评分方案进行评分。运动铊-201评分是44.3±1.2，在再分布研究中增加到47.3±1.2（p<0.001）。心肌梗死后3个月，尽管心率血压乘积显著增加，这将预示着更大的缺血缺损以及运动铊-201评分降低，但运动评分有所改善（48.3±1.1，p<0.001）。再分布评分相似，即48.9±1.0。铊-201心肌灌注的改善与8例患者（30%）应激性缺血的消失相关。这些结果表明，心肌梗死后铊-201心肌灌注显像可能会出现自发改善。
