在乙胺嗪治疗期间出现的盘尾丝虫结节。

An onchocercal nodule appearing during diethylcarbamazine therapy.

作者信息

Boye E S, Connor D H

出版信息

Am J Trop Med Hyg. 1982 Nov;31(6):1123-7. doi: 10.4269/ajtmh.1982.31.1123.

DOI:10.4269/ajtmh.1982.31.1123

Abstract

We describe the appearance of an onchocercal nodule in a patient during treatment with diethylcarbamazine (DEC). This is a unique occurrence. DEC has been employed in the treatment of onchocerciasis for many years, but there have been no reports of any effects of DEC on nodules. Histopathological studies in which nodules have been examined before and after treatment of patients with DEC have not revealed any changes induced by such treatment. The histological appearance of this nodule is described, and the probable mechanism of its enlargement is discussed.

摘要

我们描述了一名患者在接受乙胺嗪（DEC）治疗期间盘尾丝虫结节的表现。这是一种独特的情况。DEC已用于治疗盘尾丝虫病多年，但尚无关于DEC对结节有任何影响的报道。对接受DEC治疗的患者结节进行治疗前后检查的组织病理学研究未发现此类治疗引起的任何变化。本文描述了该结节的组织学表现，并讨论了其增大的可能机制。

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