Weger R V, Meier D E, Richardson C T, Feldman M, McClelland R N
Am J Surg. 1982 Dec;144(6):689-93. doi: 10.1016/0002-9610(82)90552-9.
Parietal cell vagotomy was performed in 48 patients at the Parkland Memorial Hospital and the Dallas Veterans Administration Hospital between April 1977 and January 1981. The maximum follow-up time was 50 months and the average was 28 months. Seventy-five percent of the patients were followed for more than 1 year. There were no operative deaths. Four patients (8.3 percent) had persistent postoperative side effects including two documented ulcer recurrences (4.2 percent). Acid secretion studies were reviewed to characterize the longterm effect of parietal cell vagotomy. These studies demonstrated marked postoperative reductions in gastric acid secretion. The results of this study suggest that with the simplified technique described in this paper, parietal cell vagotomy can be performed with minimal mortality and morbidity by surgical residents under direct staff supervision.
1977年4月至1981年1月期间,帕克兰纪念医院和达拉斯退伍军人管理局医院对48例患者实施了壁细胞迷走神经切断术。最长随访时间为50个月,平均为28个月。75%的患者随访时间超过1年。无手术死亡病例。4例患者(8.3%)术后有持续的副作用,其中2例有记录的溃疡复发(4.2%)。回顾胃酸分泌研究以描述壁细胞迷走神经切断术的长期效果。这些研究表明术后胃酸分泌显著减少。本研究结果表明,采用本文所述的简化技术,外科住院医师在 staff 的直接监督下可进行壁细胞迷走神经切断术,且死亡率和发病率极低。 (注:原文中“direct staff supervision”里“staff”指代不明,可能影响准确理解)