Nagasue N, Inokuchi K
Ann Chir Gynaecol. 1982;71(5):291-6.
Eighteen patients with nonresectable liver cancer were treated by dearterialization of the liver. The changes in portal vein pressure and hepatic blood flow were determined prior to the immediately after dearterialization. Portal pressure decreased by 20% in the complete and 11% in the incomplete dearterialization groups. The degree of portal pressure reduction did not differ between the patient with and without associated cirrhosis of the liver. Retention and disappearance rates of indocyanine green were improved in five, unchanged in six and deteriorated in seven patients by dearterialization. The beneficial effects on hepatic haemodynamics seen in this study were probably produced by interrupting deleterious intrahepatic arteriovenous shuntings in or around the tumors.
18例不可切除肝癌患者接受了肝脏去动脉化治疗。在去动脉化治疗前后即刻测定门静脉压力和肝血流的变化。完全去动脉化组门静脉压力下降20%，不完全去动脉化组下降11%。伴有或不伴有肝硬化的患者之间门静脉压力降低程度无差异。去动脉化治疗后，5例患者吲哚菁绿潴留率和消失率改善，6例无变化，7例恶化。本研究中观察到的对肝脏血流动力学的有益影响可能是通过中断肿瘤内或肿瘤周围有害的肝内动静脉分流产生的。
