Cameron V, Hawkins D F, Ryder T A, Mackenzie M L
Anticancer Res. 1982 Jul-Aug;2(4):187-92.
Human cervical epithelial cells, growing out in confluent monolayers from small explants, develop cytoplasmic extensions from the margins of the growth, extending out and terminating on the glass substrate. The marginal fibrils are particularly frequent on the edges of cellular lamellipodia, protruding in advance of the growing edges. Marginal cells with microvilli tend to have more marginal fibrils on their leading edges than smooth more differentiated cells, and occasionally there is continuity between microvilli and marginal fibrils. Where there is cellular overlap, marginal fibrils extending over the surface of another cell can be seen; where these is an intercellular cleft, cytoplasmic bridges have the same appearance as marginal fibrils. Colchicine (10-6 M) did not affect marginal fibril formation.
人宫颈上皮细胞从小外植体生长成汇合的单层，从生长边缘长出细胞质延伸物，延伸并终止于玻璃基质上。边缘纤维在细胞片状伪足边缘特别常见，在生长边缘之前突出。有微绒毛的边缘细胞在其前缘往往比光滑的、分化程度更高的细胞有更多的边缘纤维，微绒毛和边缘纤维之间偶尔存在连续性。在细胞重叠处，可以看到边缘纤维延伸到另一个细胞的表面；在细胞间有裂隙的地方，细胞质桥与边缘纤维外观相同。秋水仙碱（10-6 M）不影响边缘纤维的形成。
