使用选择性β-肾上腺素能受体阻滞剂对甲状腺毒症患者进行术前准备。
The use of a selective beta-adrenergic receptor blocker for the preoperative preparation of thyrotoxic patients.
作者信息
Dial P, Hastings P R
出版信息
Ann Surg. 1982 Dec;196(6):633-5. doi: 10.1097/00000658-198212001-00002.
Abstract
Metoprolol, a cardioselective beta-blocker, was used in two asthmatic, thyrotoxic patients in preparation for thyroidectomy. Adequate reduction in resting heart rate was achieved in both individuals without inducing clinically significant airway obstruction. Beta-1-blockade can be selectively employed in this clinical setting, but patients should be hospitalized and closely monitored for adverse effects on pulmonary function. Metoprolol therapy in patients with reversible airway obstruction is discussed with reference to recent studies on relative cardioselectivity.
摘要
美托洛尔是一种心脏选择性β受体阻滞剂，在两名患有哮喘且甲状腺毒症的患者中用于甲状腺切除术的术前准备。两名患者的静息心率均得到了充分降低，且未引发具有临床意义的气道阻塞。在这种临床情况下可选择性地使用β1受体阻滞剂，但患者应住院并密切监测其对肺功能的不良影响。结合近期关于相对心脏选择性的研究，对可逆性气道阻塞患者的美托洛尔治疗进行了讨论。
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本文引用的文献
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