Patterson G A, Ilves R, Ginsberg R J, Cooper J D, Todd T R, Pearson F G
Ann Thorac Surg. 1982 Dec;34(6):692-7. doi: 10.1016/s0003-4975(10)60911-3.
Thirty-five patients, 29 men and 6 women, underwent pulmonary and chest wall resection for treatment of bronchogenic cancer which had extended into the chest wall. Anterior chest wall resection was performed in 6 patients, lateral resection in 2, and posterior resection in 27. Marlex mesh was employed as a prosthetic material in 13 patients. Radiotherapy was given as part of the planned therapeutic regimen in 13 patients. Three patients (8.5%) died in the postoperative period. There was 21 late deaths. Eleven patients are alive 7 months to 12 years after resection. The overall actuarial survival, including operative mortality, is 38% at 5 years. Actuarial survival of the 13 irradiated patients is 56% at 2 and 5 years. We believe that bronchogenic carcinoma with chest wall involvement is not hopeless, and that resection of the lung and chest wall can be performed with an acceptable mortality rate.
35例患者(29例男性,6例女性)因支气管源性癌侵犯胸壁而接受了肺和胸壁切除术。6例行前胸壁切除,2例行侧胸壁切除,27例行后胸壁切除。13例患者使用Marlex网片作为假体材料。13例患者接受了放疗作为计划治疗方案的一部分。3例患者(8.5%)术后死亡。有21例晚期死亡。11例患者在切除术后7个月至12年存活。包括手术死亡率在内的5年总精算生存率为38%。13例接受放疗患者的2年和5年精算生存率为56%。我们认为,支气管源性癌侵犯胸壁并非毫无希望,肺和胸壁切除可以在可接受的死亡率下进行。